0859-38-6153
鳥取大学医学部 統合分子医化学

研究業績(論文) 2012~

2018

コエンザイムQ10による脂肪組織の代謝制御を介した抗肥満・抗糖尿病効果

堀越洋輔,倉敷達之,松浦達也. ビタミン 2018; 92(8), 381-385.

 

α-Tocopherol promotes HaCaT keratinocyte wound repair through the regulation of polarity proteins leading to the polarized cell migration.

 Horikoshi Y, Kamizaki K, Hanaki T, Morimoto M, Kitagawa Y, Nakaso K, Kusumoto C, Matsura T.   BioFactors 2018; 44(2):180-191. doi: 10.1002/biof.1414.

 

2017

 

Compound 48/80, a mast cell degranulator, causes oxidative damage by enhancing vitamin C synthesis via reduced glutathione depletion and lipid peroxidation through neutrophil infiltration in rat livers.

Ohta Y, Yashiro K, Ohashi K, Horikoshi Y, Kusumoto C, Matsura T.   J Clin Biochem Nutr 2017; 60: 187-198.

 

代謝変化に伴うCoQH2/CoQ比の増加はミトコンドリア電子伝達系におけるスーパーコンプレックスの再構築を促進する

松浦達也. ビタミン 2017; 91: 441-444.

 

2016 

Nicotine enhances the malignant potential of human pancreatic cancer cells via activation of atypical protein kinase C.

Hanaki T, Horikoshi Y, Nakaso K, Nakasone M, Kitagawa Y, Amisaki M, Arai Y, Tokuyasu N, Sakamoto T, Honjo S, Saito H, Ikeguchi M, Yamashita K, Ohno S, Matsura T.  Biochim Biophys Acta 2016;1860: 2404-2415.

 

Estrogen receptor-mediated effect of δ-tocotrienol prevents neurotoxicity and motor deficit in the MPTP mouse model of Parkinson's disease.

Nakaso K, Horikoshi Y, Takahashi T, Hanaki T, Nakasone M, Kitagawa Y, Koike T, Matsura T.   Neurosci Lett 2016; 610: 117-122.

 

Allele-specific regulation of mutant Huntingtin by Wig1, a downstream target of p53.

Kim SH, Shahani N, Bae BI, Sbodio JI, Chung Y, Nakaso K, Paul BD, Sawa A.  Hum Mol Genet 2016 (in press)

 

Rice Bran Dietary Supplementation Improves Neurological Symptoms and Loss of Purkinje Cells in Vitamin E-deficient Mice.

Takahashi T, Nakaso K, Horikoshi Y, Hanaki T, Yamakawa M, Nakasone M, Kitagawa Y, Matsura T.    Yonago Acta Med 2016; 59: 188-195.

 

Preconditioning by low dose LPS prevents subsequent LPS-induced severe liver injury via Nrf2 activation in mice.

Nakasone M, Nakaso K, Horikoshi Y, Hanaki T, Kitagawa Y, Takahashi T, Inagaki Y, Matsura T.   Yonago Acta Med 2016; 59: 223-231.

 

2015

Effect of Dietary Vitamin E Supplementation on Liver Oxidative Damage in Rats with Water-Immersion Restraint Stress.

Ohta Y, Yashiro K, Ohashi K, Horikoshi Y, Kusumoto C, Matsura T, Fukuzawa K.     J Nutr Sci Vitaminol (Tokyo)  2015; 61: 113-122.

 

Aberrant activation of atypical protein kinase C in carbon tetrachloride-induced oxidative stress provokes a disturbance of cell polarity and sealing of bile canalicular lumen.

Horikoshi Y, Kitatani K, Toriumi K, Fukunishi N, Itoh Y, Nakamura N, Ohno S, Matsura T, Takekoshi S.   Am J Pathol 2015; 185: 958-968.

 

Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington's model mice.

Kurosawa M, Matsumoto G, Kino Y, Okuno M, Kurosawa-Yamada M, Washizu C, Taniguchi H, Nakaso K, Yanagawa T, Warabi E, Shimogori T, Sakurai T, Hattori N, Nukina N.    Hum Mol Genet   2015; 24: 1092-1105.

 

ATP産生

松浦達也. コエンザイムQ10の基礎と応用(日本コエンザイムQ協会編), 丸善プラネット, 2015, p11-24.

 

2014

The estrogen receptor β-PI3K/Akt pathway mediates the cytoprotective effects of tocotrienol in a cellular Parkinson's disease model.

Nakaso K, Tajima N, Horikoshi Y, Nakasone M, Hanaki T, Kamizaki K, Matsura T.   Biochim Biophys Acta 2014; 1842 :1303-1312.

 

Oxidized phosphatidylserine: production and bioactivities.

Matsura T.  Yonago Acta Med 2014; 57(4):119-127.

 

2013

Vitamin E depletion enhances liver oxidative damage in rats with water-immersion restraint stress.

Ohta Y, Yashiro K, Ohashi K, Imai Y, Kusumoto C, Matsura T, Hidaka M, Fukuzawa K.   J Nutr Sci Vitaminol (Tokyo)  2013; 59: 79-86.

 

Dopamine-mediated oxidation of methionine 127 in α-synuclein causes cytotoxicity and oligomerization of α-synuclein.

Nakaso K, Tajima N, Ito S, Teraoka M, Yamashita A, Horikoshi Y, Kikuchi D, Mochida S, Nakashima K, Matsura T.      PLoS One  2013; 8: e55068. doi: 10.1371/journal.pone.0055068. 

 

Deficiency of p62/Sequestosome 1 causes hyperphagia due to leptin resistance in the brain.

Harada H, Warabi E, Matsuki T, Yanagawa T, Okada K, Uwayama J, Ikeda A, Nakaso K, Kirii K, Noguchi N, Bukawa H, Siow RC, Mann GE, Shoda J, Ishii T, Sakurai T.            J Neurosci 2013; 33: 14767-14777.

 

2012

Cytoprotective effect of chlorogenic acid against α-synuclein-related toxicity in catecholaminergic PC12 cells.

Teraoka M, Nakaso K, Kusumoto C, Katano S, Tajima N, Yamashita A, Zushi T, Ito S, Matsura T.      J Clin Biochem Nutr  2012; 51: 122-127.

 

Mechanisms underlying production and externalization of oxidized phosphatidylserine in apoptosis: involvement of mitochondria.

Yamashita A, Morikawa H, Tajima N, Teraoka M, Kusumoto C, Nakaso K, Matsura T.     Yonago Acta Med 2012; 55: 11-20.

 

Parkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cells.

Jiang H, Ren Y, Yuen EY, Zhong P, Ghaedi M, Hu Z, Azabdaftari G, Nakaso K, Yan Z, Feng J.       Nat Commun 2012; 3: 668. doi: 10.1038/ncomms1669.